Herpes gestationis. Immunopathology and characterization of the HG factor.

Herpes gestationis. Immunopathology and characterization of the HG factor.

Five patients with herpes gestationis, a blistering disease of pregnancy, were studied immunologically. All had in vivo deposition of C3 in a linear band along the basement membrane zone of lesional and normal-appearing skin, the location of early blister formation. Immunoglobulin deposition was more variable, though four patients had evidence of in vivo bound IgG at the same site. A circulatin...

The immunopathology of herpes gestationis. Immunofluorescence studies and characterization of "HG factor".

Nine skin biopsies from seven herpes gestationis patients were studied by immunofluorescence (IF) techniques. Basement membrane zone (BMZ) deposition of C3 and properdin was present in all nine skin specimens, while IgG deposition was apparent in only one. With in vitro C3 IF staining, positive BMZ staining (HG factor activity) was noted with all seven of our patients' serum samples tested. By ...

Herpes gestationis = لوبقعلا يلمحلا Pemphigoid Gestationis Herpes Gestationis

Herpes gestationis = لوبقعلا يلمحلا Pemphigoid Gestationis Herpes Gestationis

Herpes gestationis = لوبقعلا يلمحلا Pemphigoid Gestationis Herpes Gestationis